Whither compassionate leadership? A systematic review

Recent disastrous events, such as the COVID-19 pandemic, has amplified the appeal for compassionate leadership in organizations and is viewed as the need of the hour. While compassion is a timeless concept, there appears to be a lack of clarity around the idea of compassionate leadership, and the current understanding appears limited, fragmented, and scattered across the literature. This integrative systematic review of 41 articles during the last 20 years (2002–2021) conceptualizes six critical dimensions of compassionate leadership, namely: empathy;openness and communication;physical, mental health and well-being;inclusiveness;integrity;respect and dignity. These findings enhance our understanding of how organizational leaders can effectively incorporate the dimensions to become compassionate leaders. The review examines how compassionate leadership is defined and understood in the literature, and a contribution in the form of a definition for compassionate leadership is offered. Finally, gaps in the literature are highlighted, offering avenues for future research, along with implications for research, theory, and practice. © 2023, The Author(s).

Assessment of knowledge and attitude among pediatric dentists regarding spread and control of infection before and after COVID-19 crisis

Background: In this time of COVID-19 crisis, need of hour to appropriately perform dental procedures to reduce the spread of this deadly disease, it is importance to assess the knowledge and attitude of pediatric dentists regarding spread and control of infection before and after COVID-19 crisis. Methods and Materials: Questionnaire-based survey composed of 6 questions that assess the knowledge of pediatric dentists regarding COVID-19 infection and 10 questions each designed to gather information about their clinical practice before and after COVID-19 crisis which shows attitude of pediatric dentists. Online survey link was circulated through social media and an e-mail to pediatric dentists from different locations in India and the responses were collected. 346 pediatric dentists willingly responded in the study. Result(s): On grading the knowledge score according to the number of most appropriate responses chosen by the respondents, it was found that 82.4% of the pediatric dentist had good knowledge regarding the COVID-19 infection, 16.4% had fair and 1.2% had poor knowledge about it. The attitude regarding clinical practice of pediatric dentists, before and after COVID-19 crisis, is shown in percentage and was determined and compared using Chi-square test. Conclusion(s): Our study presented data on the depth of knowledge and the attitude among the pediatric dentists' attitude regarding spread and control of infection before and after COVID-19 crisis it was quite acceptable.Copyright © 2020 Ubiquity Press. All rights reserved.

Differentiating Multisystem Inflammatory Syndrome in Children (MIS-C) and Its Mimics - A Single-Center Experience From a Tropical Setting

OBJECTIVES: Identifying clinical and laboratory indicators that differentiate multisystem inflam-matory syndrome in children (MIS-C) apart from other febrile diseases in a tropical hospital setting. METHOD(S): Review of hospital records done in a tertiary care exclusive children's hospital for children admitted from April, 2020 till June, 2021. Laboratory values, severe acute respiratory syndrome coronavirus (SARS-CoV-2) serological status, and clinical signs and symptoms of patients with MIS-C, and those with similar presentations were analyzed. RESULT(S): 114 children fulfilled the inclusion criteria (age group of 1 mo-18 y) for whom a diagnosis of MIS-C was considered in the emergency room based on the clinical features. Among them, 64 children had the final diagnosis of MIS-C, and the remaining 50 children had confirmatory evidence of infections mimicking MIS-C such as enteric fever, scrub typhus, dengue and appendicitis. CONCLUSION(S): Older age group, presence of muco-cutaneous symptoms, very high C-reactive protein, neutrophilic leukocytosis, abdominal pain and absence of hepatosplenomegaly favor a diagnosis of MIS-C.

Differentiating Multisystem Inflammatory Syndrome in Children (MIS-C) and Its Mimics - A Single-Center Experience From a Tropical Setting.

OBJECTIVE: Identifying clinical and laboratory indicators that differentiate multisystem inflam-matory syndrome in children (MIS-C) apart from other febrile diseases in a tropical hospital setting. METHODS: Review of hospital records done in a tertiary care exclusive children's hospital for children admitted from April, 2020 till June, 2021. Laboratory values, severe acute respiratory syndrome coronavirus (SARS-CoV-2) serological status, and clinical signs and symptoms of patients with MIS-C, and those with similar presentations were analyzed. RESULTS: 114 children fulfilled the inclusion criteria (age group of 1 mo-18 y) for whom a diagnosis of MIS-C was considered in the emergency room based on the clinical features. Among them, 64 children had the final diagnosis of MIS-C, and the remaining 50 children had confirmatory evidence of infections mimicking MIS-C such as enteric fever, scrub typhus, dengue and appendicitis. CONCLUSION: Older age group, presence of muco-cutaneous symptoms, very high C-reactive protein, neutrophilic leukocytosis, abdominal pain and absence of hepatosplenomegaly favor a diagnosis of MIS-C.

Age Structured Mathematical Modeling Studies on COVID-19 with respect to Combined Vaccination and Medical Treatment Strategies

In this study, we develop a mathematical model incorporating age-specific transmission dynamics of COVID-19 to evaluate the role of vaccination and treatment strategies in reducing the size of COVID-19 burden. Initially, we establish the positivity and boundedness of the solutions of the non controlled model and calculate the basic reproduction number and do the stability analysis. We then formulate an optimal control problem with vaccination and treatment as control variables and study the same. Pontryagin's Minimum Principle is used to obtain the optimal vaccination and treatment rates. Optimal vaccination and treatment policies are analysed for different values of the weight constant associated with the cost of vaccination and different efficacy levels of vaccine. Findings from these suggested that the combined strategies (vaccination and treatment) worked best in minimizing the infection and disease induced mortality. In order to reduce COVID-19 infection and COVID-19 induced deaths to maximum, it was observed that optimal control strategy should be prioritized to the population with age greater than 40 years. Varying the cost of vaccination it was found that sufficient implementation of vaccines (more than 77 %) reduces the size of COVID-19 infections and number of deaths. The infection curves varying the efficacies of the vaccines against infection were also analysed and it was found that higher efficacy of the vaccine resulted in lesser number of infections and COVID induced deaths. The findings would help policymakers to plan effective strategies to contain the size of the COVID-19 pandemic. © 2022 Bishal Chhetri et al., published by De Gruyter.

Using Technology to Overcome the Challenges of COVID-19 Pandemic in India: The DEMCARES Model of Virtual Intervention Delivery

BACKGROUND: The COVID-19 pandemic and associated restrictions have greatly affected the delivery of treatment and access to in-person interventions for dementia, especially in low- and middle-income countries such as India. Technology use could potentially help bring the above-mentioned services to persons with dementia (PwD) and their caregivers in the safety of their homes. The aim of this study is to evaluate the dementia care services delivered by the Dementia Care in SCARF (DEMCARES) team in the densely populated city of Chennai in South India during the COVID-19 pandemic.

An enabling framework for blockchain in tourism

This viewpoint article proposes an enabling framework that identifies the use of various blockchain technologies in tourism and their applications (digitalization, automation, disintermediation, and intelligent environment) across the different stages of travel (pre-trip, during the trip, and post-trip). As we know, the tourism sector contributes immensely to world GDP and job creation. However, the COVID-19 pandemic, even after two years since it first appeared, continues to adversely impact the tourism prospects of countries across the world due to nationwide lockdowns and travel restrictions. As the world tries to adapt to the "new normal," the tourism sector is forced to re-think its ways of doing business and bring about innovations to facilitate the new norms of contactless and safe transactions. Also, the sector, more than ever, need to effectively deal with its inherent challenges such as transparency and credibility of information, fraudulent practices, opportunistic behavior of intermediaries, and foreign currency risks. Blockchain technology can transform the tourism sector by offering innovative solutions that address its pressing issues. However, our current understanding of blockchain application in tourism is quite limited, with previous work being largely fragmented and narrow in terms of both scope and application. We foresee that the insights offered in this viewpoint, including the framework, will advance both theory and practice and facilitate the implementation of blockchain-enabled solutions across different travel stages.

Disposable biosensors based on metal nanoparticles.

The coronavirus disease2019 (COVID-19) pandemic has highlighted the need for disposable biosensors that can detect viruses in infected patients quickly due to fast response and also at a low cost.The present review provides an overview of the applications of disposable biosensors based on metal nanoparticles in enzymatic and non-enzymatic sensors with special reference to glucose and H2O2, immunosensors as well as genosensors (DNA biosensors in which the recognized event consists of the hybridization reaction)for point-of-care diagnostics. The disposable biosensors for COVID19 have also been discussed.

Coronavirus Disease 2019 (COVID-19) Vaccination for Children: Position Statement of Indian Academy of Pediatrics Advisory Committee on Vaccination and Immunization Practices

Justification Data generated after the first wave has revealed that some children with Coronavirus 19 (COVID-19) can become seriously ill. Multi-inflammatory syndrome in children (MIS-C) and long COVID cause significant morbidity in children. Prolonged school closures and quarantine have played havoc with the psychosocial health of children. Many countries in the world have issued emergency use authorisation (EUA) of selected COVID-19 vaccines for use in children. In India, a Subject Expert Committee (SEC) has recommended the use of Covaxin (Bharat Biotech) for children from the ages of 2-18 years. The recommendation has been given to the Drugs Controller General of India (DCGI) for final approval. Objective To provide an evidence-based document to guide the pediatricians on the recommendation to administer COVID vaccines to children, as and when they are available for use. Process Formulation of key questions was done by the committee, followed by review of literature on epidemiology and burden of COVID-19 in children, review of the studies on COVID vaccines in children, and the IAP stand on COVID-19 vaccination in children. The available data was discussed in the ACVIP focused WhatsApp group followed by an online meeting on 24 October, 2021, wherein the document was discussed in detail and finalized. Recommendations The IAP supports the Government of India's decision to extend the COVID-19 vaccination program to children between 2-18 years of age. Children with high-risk conditions may be immunized on a priority basis. The IAP and its members should be a partner with the Government of India, in the implementation of this program and the surveillance that is necessary following the roll-out.

Significance of Sialoglycans in SARS-CoV2 Infection Comment

The second wave of coronavirus disease 19 (COVID-19) has hit India badly with a rapid surge of cases. One of the greatest challenges in managing infections from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the incomplete knowledge regarding the disease course, hypersensitivity, and relative resistance in a number of individuals. Recently, it has been reported that besides the Angiotensin-converting enzyme 2 (ACE2), certain sialic acids present on the cell surface may also function as potential receptors for binding the spike protein of SARS-CoV-2. In this brief commentary we briefly discuss the role of sialic acids in SARS-CoV-2 infection and suggest more research investigations pertaining to this arena. This may pave the way for breakthrough solutions to combat the current pandemic more effectively by developing specific drug-targeted therapies.

PERCEIVED STRESS AND COPING AMONG ONCOLOGY HEALTH CARE WORKERS (OHCW) DURING THE COVID-19 PANDEMIC IN A TERTIARY CANCER CENTRE IN INDIA

Objective: The objective of the study is to estimate the level of the COVID-19 related stress and perceived stress and the pattern of coping styles among Oncology Health Care Workers (OHCW) during the COVID-19 pandemic. Patients and Methods: The cross-sectional study was conducted in a tertiary cancer centre in the rural part of Kerala (India). The OHCW working in the centre during the COVID-19 pandemic were included, andstudents and observers were excluded from the study. The COVID-19 stress rating scale, perceived stress scale and brief-COPE were used to collect the data. Results: Data were collected when the COVID-19 cases were in their first peak in Kerala. Two hundred and eighty two OHCW participated in the study. The COVID-19 stress of 5 or above was reported by 48.6% of OHCW. More than half (59.6%) of them reported moderate to severe perceived stress. On the Brief-COPE scale, the mean score of approach coping was 35.58 and of avoidance coping was 24.26. A significant positive correlation (r =0.347) was found between COVID-19 related stress and perceived stress. Significantly high stress was found among males, front office staff, those between 30 and 40 years, with a history of the COVID-19 contact and those with co-morbidity. Conclusions: Although half of the OHCW reported high COVID-19 related stress and perceived stress, they used an approach coping style to deal with the stress during this pandemic.

Purulent pericarditis can be near fatal

A previously healthy 27 years-old male presented with 2 weeks of substernal chest pain, progressive dyspnea, palpitations, dizziness, and(&) fever. On exam, he had tachypnea & tachycardia, was hypotensive with an elevated JVP & muffled heart sounds. Labs showed elevated WBC, CRP, lactate & high sensitive troponin. Negative for COVID-19, flu. EKG showed sinus tachycardia. CT showed large pericardial effusion with gas in the pericardial space. Echo (Figure 1) revealed large pericardial effusion with tamponade. Emergent pericardiocentesis was performed draining a liter of straw-colored thick fluid (fluid: serum LDH >3) (Figure 2). Cultures grew Strep. Anginosus & Propionibacterium acnes. Extensive infectious & immunological workup returned negative. He had initially improved on broad-spectrum antibiotics however declined clinically on day 5. Repeat CT (Figures 3 & 4) showed recurrent pericardial effusion & mediastinal abscess with trace extravasation of contrast from the esophagus to posterior mediastinum. We present a case of esophageal perforation leading to Pyopneumopericardium. Stephenson et al. reported a case series of 13 patients with esophagopericardial fistulas & pyopneumopericardium with a 100% mortality rate. Another case series showed survival rates of only 17% in 60 patients with pyopneumopericardium secondary to esophageal perforation. Erosion of esophageal ulcers, ingestion of foreign body, iatrogenic, trauma, malignancy, localized inflammation can lead to esophageal perforation. Streptococcus pneumoniae & Staphylococcus aureus are common pathogens involved. Constrictive pericarditis is a possible complication in up to 20 to 30%. Our patient underwent pericardial window & surgical debridement followed by EGD-guided gastro-jejunal tube placement. He did well after 4 weeks of IV antibiotics. Our case demonstrates that early recognition & intervention can favorably alter the course of this potentially fatal cardiac condition.

Coronavirus Disease 2019 (COVID-19) Vaccination for Children: Position Statement of Indian Academy of Pediatrics Advisory Committee on Vaccination and Immunization Practices

JUSTIFICATION: Data generated after the first wave has revealed that some children with coronavirus 19 (COVID-19) can become seriously ill. Multi-inflammatory syndrome in children (MIS-C) and long COVID cause significant morbidity in children. Prolonged school closures and quarantine have played havoc with the psychosocial health of children. Many countries in the world have issued emergency use authorisation (EUA) of selected COVID-19 vaccines for use in children. In India, a Subject Expert Committee (SEC) has recommended the use of Covaxin (Bharat Biotech) for children from the ages of 2-18 years. The recommendation has been given to the Drugs Controller General of India (DCGI) for final approval. OBJECTIVE: To provide an evidence-based document to guide the pediatricians on the recommendation to administer COVID vaccines to children, as and when they are available for use. PROCESS: Formulation of key questions was done by the committee, followed by review of literature on epidemiology and burden of Covid-19 in children, review of the studies on COVID vaccines in children, and the IAP stand on Covid-19 vaccination in children. The available data was discussed in the ACVIP focused WhatsApp group followed by an online meeting on 24 October, 2021, wherein the document was discussed in detail and finalized. RECOMMENDATIONS: The IAP supports the Govt. of India's decision to extend the COVID-19 vaccination program to children between 2-18 years of age. Children with high-risk conditions may be immunized on a priority basis. The IAP and its members should be a partner with the Government of India, in the implementation of this program and the surveillance that is necessary following the roll-out.

Exhaled Bioaerosols from Asymptomatic COVID-19 carriers- A Potential Risk in Orthodontics? Comment

The current manuscript sheds light on the possible role of bioaerosols (from mouth breathing) that may serve as vectors for transmitting COVID-19 in asymptomatic carriers reporting to dental hospitals and, hence, may pose a great challenge for even a simple orthodontic diagnosis. Further, we would like to add a few preventive considerations for containment of this novel disease spread via bioaerosols emitted, particularly during mouth breathing.

Low temperatures or high isolation delay increases the average COVID-19 infections in India: A Mathematical modeling approach

The dynamics of COVID-19 in India are captured using a set of delay differential equations by dividing a population into five compartments. The Positivity and Boundedness of the system is shown. The Existence and Uniqueness condition for the solution of system of equations is presented. The equilibrium points are calculated and stability analysis is performed. Sensitivity analysis is performed on the parameters of the model. Bifurcation analysis is performed and the critical delay is calculated. By formulating the spread parameter as a function of temperature, the impact of temperature on the population is studied. We concluded that with the decrease in temperature, the average infections in the population increases. In view of the coming winter season in India, there will be an increase in new infections. This model falls in line with the characteristics that increase in isolation delay increases average infections in the population. © 2021 D Bhanu Prakash et al.

Breastfeeding and coronavirus disease 2019 (COVID-19) vaccination: position statement of Indian Academy of Pediatrics Advisory Committee on Vaccination and Immunization Practices

Justification: In India, till recently, breastfeeding women have been excluded from the coronavirus disease (COVID-19) vaccination program, rendering a significant population of the country, including frontline workers, ineligible to derive the benefits of the COVID-19 vaccine rollout.